Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts

Authors

  • Levitah C. Mapatac Caraga State University

DOI:

https://doi.org/10.32871/rmrj1503.02.09

Keywords:

Ficus nota, phytochemical screening, cytotoxicity and histochemical test

Abstract

Tubog, Ficus nota (Blanco) Merr a rare tree in the Philippines and was found in Barangay Tambis, Barobo, Surigao del Sur. The present study designed to evaluate the antibacterial activities of Tubog,Ficus nota (Blanco) Merr fruit and leaves with ethanolic extracts. Preliminary phytochemical and histochemical studies were carried out. The antimicrobial activity of the fruit extract against pathogenic strains evaluated based on the zone of inhibition using paper disc diffusion method with tested bacteria of Escherichia coli ATTC 25922, Staphylococcus aureus ATTC 25923, Klebsiella pneumonia UPCC 1360, and Salmonella typhimurium UPCC 1368.The qualitative phytochemical tests exhibited the presence of common bioactive compounds including alkaloids, tannins, flavonoids, saponins, flavonoids and anthraquinones. The aqueous extract has shown high activity in ethanolic extract has shown significantly good activity when compared to standard chemotherapeutic agent Chloramphenicol. Based on the result it was concluded that Ficus nota are rich in bioactive components and exhibits antimicrobial activity against pathogens. Cytotoxicity result showed higher toxicity with the fruit compared with ficus nota leaves ethanolic extract.

Author Biography

Levitah C. Mapatac, Caraga State University

an Associate Professor III of College of Arts and
Sciences in Caraga State University, Ampayon, Butuan City. She received her Doctor in Philosophy in Science Education (Chemistry) last April 2016 at University of Science and Technology of Southern Philippines, Cagayan de Oro City. She had been with various research endeavors especially with the traditional medicines of the IP’s in Caraga region, a project assistant in the DOST-PCCIERD
funded under the Contamination Pathway in Mindanao delving in the Artisanal Small Scale Mining in Caraga region. She had made different educational researches, a thesis adviser, and a consultant in Science Investigatory Projects. She had presented most of her research outputs in an international and national forum and one of them was funded by CHED in International Conference on Advances in Plant Sciences at Chiangmai, Thailand.

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Published

2015-12-03

How to Cite

Mapatac, L. C. (2015). Antibacterial, Histochemical and Phytochemical Screening and Cytotoxicity Activity of Tubog, Ficus nota (Blanco) Merr Leaf and Fruit Extracts. Recoletos Multidisciplinary Research Journal, 3(2). https://doi.org/10.32871/rmrj1503.02.09

Issue

Vol. 3 No. 2 (2015)

Section

Articles

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